Revealing Cellular Dynamics with Millisecond Precision – The New Tool That Turned Electron Micrographs into Motion Pictures of Neural Communication

Dr. Shigeki Watanabe

Associate professor of cell biology, Johns Hopkins School of Medicine, Solomon H. Snyder Department of Neuroscience

Dr. Frédéric Leroux

Advanced workflow specialist, Leica Microsystems

In this tutorial:

  • What if you can dissect the cellular dynamics with millisecond precision?
  • What if you can unravel the morphological transformation of a neuron millisecond by millisecond using electron microscopy?
  • Could this be even possible?

In this webinar, we will talk about how optogenetics coupled with high-pressure freezing can make this possible.

We will discuss how to implement electrical stimulation and why it is superior to light stimulation.

We will also discuss the importance of sample processing and the challenges you would face while freezing different types of samples.

View the webinar replay to hear the story of discovery by our speakers Dr. Watanabe and Dr. Leroux.

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