Imaging Blood-Brain Barrier Permeability For Neurotherapeutic Delivery

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Afraa Alzoubi

PhD Student, Imperial College London

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Recorded live from Imperial College London.

Afraa Alzoubi and her colleagues use focused ultrasound and microbubbles to facilitate the passage of drugs across the blood-brain barrier. In this short case study, Afraa shows how they use fluorescent imaging to confirm drug delivery into brain parenchyma and color imaging of stained sections to look at tissue morphology. She also shows how they can switch quickly between these different imaging modes using the Mica Imaging Microhub from Leica Microsystems.

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